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A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.



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Hidroclorotiazida 50 mg para q sirve a Drugs class: Antipsychotics, Benzodiazepines Clinical trials conducted Study design: Randomised, double-blind, prospective trial including 602 patients aged 21 years and older with schizophrenia Intervention: Treatment with haloperidol 40 mg qd. for three months Outcome: Mean ± SD change in Beck Anxiety Inventory and Clinician Global Impression Scale at 3-month intervals (CGI-SSI and CGI-S) vs placebo at 6-month intervals (P= 0.0229) Differences in baseline values between Haloperidol and placebo groups at 1-year intervals: Haloperidol versus placebo - mean differences -22.4 pts (P< 0.0001 vs placebo) and -6.3pts (P= 0.0269 vs placebo); Haloperidol versus 40 mg qd. - mean differences -16.7 pts (P<0.0204 vs placebo) and -9.3 pts (P= 0.0503 vs placebo); Haloperidol versus 40 mg qd. + placebo - mean differences -10.4 pts (P= 0.0029 vs placebo) and -5.4 pts (P= 0.0209 vs placebo) Conclusion: Haloperidol is a safe and effective drug with a favorable safety profile and dose-limiting adverse effect. 5. Zofran Route of administration: IV Side effect profile: Zofran is associated with nausea, vomiting and diarrhea, which may be dose limiting Drugs class: Antipsychotics Clinical trial conducted Comparisons: Zofran versus placebo (in addition to a no-treatment control group) Population studied: Outpatients aged 20 yr and older, assessed clinically by two psychiatrist trained clinicians who did not know the participant's diagnosis or condition Intervention: Zofran 40 mg qd. Outcome: Significant increase in positive symptoms (total score: 28.6 vs 19.1; n=30); improvement in positive symptom severity scores (P=0.04 vs placebo); no effect on negative symptoms Summary of clinical findings: Zofran 40 mg qd. is effective in adults with psychosis and has a favorable side effect profile (less nausea or vomiting and nz online pharmacy com fewer diarrhea) as compared with haloperidol (n=25). This is the first placebo- and treatment-controlled study that demonstrates positive symptom changes following dose increase of amlodipino con hidroclorotiazida precio Zofran relative to placebo. 6. Quetiapine Route of administration: Oral Side effect profile: Rare drug-related skin rash at the site of an injection, most likely a consequence of the presence diazepam by way of osmotic release Drugs class: Antipsychiatrists Population studied: Outpatients from the General practice clinical trial (NCT01037122), who were randomized to either placebo (7/9) or quetiapine 15 mg/45 mg qd.(15/17) Intervention: Treatment with oral quetiapine 20 mg qd. for 6 consecutive weeks. Main Outcome Measure: The Clinical Global Impression (cGI) Scale: 8th version; a global rating of improvement "very much improved" or "improved" by the end of trial. Results: The effect sizes are small in a trial sample of only 12 patients, indicating very unclear evidence for the drug's ability to improve positive symptoms at least in some patients. The effect sizes are small. medium. Both of these are very good results from a poorly powered study. These results are at odds with the results of Cochrane review, whose conclusion was that quetiapine does not have the potential to treat psychotic disturbances. Furthermore, quetiapine's side effects such as somnolence, dizziness or headache have been reported for some patients. Conclusion: This trial showed that in a highly selected patient population (elderly, at high risk for psychiatric disturbance) the benefit of quetiapine over placebo appeared to be minimal and the potential clinical harms of such side effects were considerable. Further, the authors of this review should be ashamed of themselves for implying that the negative effects of quetiapine outweigh its potential benefits. They should retract this conclusion and apologize to their colleagues who would have been adversely affected by this nonsense. The only benefit is anecdotal: anecdotal case of one person who got really sick when they took quetiapine. 7. Aripiprazole Side effect profile: Seizures, gastrointestinal disturbance, dizziness, and insomnia

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